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Istradefylline 40 mg/day greater peak ranges and AUC of CYP3A4 substrates in medical trials. This influence wasn't observed with istradefylline 20 mg/day. Take into account dose reduction of sensitive CYP3A4 substrates.Clients enrolled in these experiments had a analysis of OSA, SWD, or narcolepsy and have been necessary to fulfill accepted criteri

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